Article No
AMB-3A6APM-100
CRTC3 Primary Antibody
CRTC3 Primary Antibody
Antibodies Primary
Specifications
| MW | 68kDa |
| Application | WB, ELISA, ICC |
| Article No | AMB-3A6APM-100 |
| Biosite Brand | Biosite mAb |
| Country Availability | all |
| Clone | 5G9 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | CRTC3 Primary Antibody |
| Supplier | Nordic Biosite |
| Entrez Gene ID | 64784 |
| Format | Ascitic fluid containing 0.03% sodium azide. |
| Immunogen | Purified recombinant fragment of human CRTC3 expressed in E. Coli. |
| Isotype | IgG1 |
| Notes | Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR) .Tissue specificity: Predominantly expressed in B and T lymphocytes. Highest levels in lung. Also expressed in brain, colon, heart, kidney, ovary, and prostate. Weak expression in liver, pancreas, muscle, small intestine, spleen and stomach. |
| Alias Names | TORC3; FLJ21868; CRTC3 |
| Previous Article No | AMB-8607 |
| Product Type | Antibodies Primary |
| Protocol | ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000 |
| Size | 100µl |
| Source / Host | mouse |
| Species Reactivity | human, monkey |
| Storage | 4°C -20°C for long term storage |
| Substrate / Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Technical Specifications | ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000 |
| Product Page Updated | 2024-01-25T14:27:22.065Z |
