STK11

Article No AMB-8577
Product Type Antibodies Primary
Application ELISA, WB, FC
Size 100μl

Specifications

MW 54kDa
Country Availability all
BioSite Brand BioSite mAb
Clone 4H12;
Clone Type monoclonal
Description Mouse Monoclonal Antibody to STK11
Supplier BioSite Mab
Entrez Gene ID 6794
Immunogen Purified recombinant fragment of human STK11 expressed in E. Coli. ; ;
Isotype IgG1
Notes Essential role in G1 cell cycle arrest. Phosphorylates and activates members of the AMPK-related subfamily of protein kinases. Tumor suppressor.serine/threonine kinase 11,with two alternatively spliced isoforms,expressed in all tissues,strongly homolog of Xenopus early embryonic kinase 1 (XEEK1),tumor suppressor gene in hamartomas syndrome and in left sided colon carcinogenesis,mutated in sporadic testicular cancer,malignant melanomas and laryngeal tumors,playing a minor role in the development of ovarian carcinoma.LKB1 is a potential target for atherosclerosis and cancer and is shown to be mutated in patients with Peutz-Jeghers cancer syndrome. Tissue specificity: Ubiquitously expressed. Strongest expression in testis and fetal liver.
Alias Names PJS; LKB1; STK11
Protocol ELISA: 1/10000; WB: 1/500 - 1/2000; FCM: 1/200 - 1/400
Source / Host mouse
Species Reactivity human, mouse, monkey
Storage 4 C, -20 C for long term storage
Substrate / Buffer Ascitic fluid containing 0.03% sodium azide. ; ;
Technical Specifications ELISA: 1/10000; WB: 1/500 - 1/2000; FCM: 1/200 - 1/400
Product Page Updated 2018-10-15T09:15:17.802Z

Shipping info

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Source/Host:

mouse mouse

Species reactivity:

human, mouse, monkey human mouse monkey

Suggested protocols:

Western Blot

Western Blot