Article No
AMB-1NHMRB-100
STAT3 Primary Antibody
STAT3 Primary Antibody
Antibodies Primary
Specifications
| MW | 88kDa |
| Application | WB, ELISA, ICC |
| Article No | AMB-1NHMRB-100 |
| Biosite Brand | Biosite mAb |
| Country Availability | all |
| Clone | 3B5 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | STAT3 Primary Antibody |
| Supplier | Nordic Biosite |
| Entrez Gene ID | 6774 |
| Format | Ascitic fluid containing 0.03% sodium azide. |
| Immunogen | Purified recombinant fragment of human STAT3 expressed in E. Coli. |
| Isotype | IgG1 |
| Notes | The Stat3 transcription factor is an important signaling molecule for many cytokines and growth-factor receptors and is required for murine fetal development . Stat3 is constitutively activated in a number of human tumors and possesses oncogenic potential and anti-apoptotic activities. Stat3 is activated by phosphorylation at Tyr705, which induces dimerization, nuclear translocation and DNA binding. Transcriptional activation seems to be regulated by phosphorylation at Ser727 through the MAPK or mTOR pathways. Stat3 isoform expression appears to reflect biological function as the relative expression levels of Stat3a (86 kDa) and Stat3 |
| Alias Names | APRF; HIES; FLJ20882; MGC16063; STAT3 |
| Previous Article No | AMB-8560 |
| Product Type | Antibodies Primary |
| Protocol | ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000 |
| Size | 100µl |
| Source / Host | mouse |
| Species Reactivity | human, mouse, monkey |
| Storage | 4°C -20°C for long term storage |
| Substrate / Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Technical Specifications | ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000 |
| Product Page Updated | 2024-01-25T14:27:22.065Z |
