CD86

Article No AMB-8545
Product Type Antibodies Primary
Application ELISA, WB
Size 100μl

Specifications

MW 52kDa
Country Availability all
BioSite Brand BioSite mAb
Clone 1B3;
Clone Type monoclonal
Description Mouse Monoclonal Antibody to CD86
Supplier BioSite Mab
Entrez Gene ID 942
Immunogen Purified recombinant fragment of human CD86 expressed in E. Coli.
Isotype IgG1
Notes This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined.Tissue specificity: Expressed by activated B-lymphocytes and monocytes.
Alias Names B70; B7-2; LAB72; CD28LG2; MGC34413; CD86
Protocol ELISA: 1/10000; WB: 1/500 - 1/2000
Source / Host mouse
Species Reactivity human
Storage 4 C, -20 C for long term storage
Substrate / Buffer Ascitic fluid containing 0.03% sodium azide.
Technical Specifications ELISA: 1/10000; WB: 1/500 - 1/2000
Product Page Updated 2018-10-15T09:15:17.802Z

Shipping info

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Source/Host:

mouse mouse

Species reactivity:

human human

Suggested protocols:

Western Blot

Western Blot