Article No
AMB-Z7C9WT-100
GFI1 Primary Antibody
GFI1 Primary Antibody
Antibodies Primary
Specifications
| MW | 45kDa |
| Application | WB, ELISA |
| Article No | AMB-Z7C9WT-100 |
| Biosite Brand | Biosite mAb |
| Country Availability | all |
| Clone | 5D7 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | GFI1 Primary Antibody |
| Supplier | Nordic Biosite |
| Entrez Gene ID | 2672 |
| Format | Ascitic fluid containing 0.03% sodium azide. |
| Immunogen | Purified recombinant fragment of human GFI1 expressed in E. Coli. |
| Isotype | IgG1 |
| Notes | This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.Expression of GFl1 ranges from the hematopoietic and lymphoid system, to sensory epithelia, lung and parts of the CNS. |
| Alias Names | SCN2; GFI-1; ZNF163; FLJ94509; GFI1 |
| Previous Article No | AMB-8536 |
| Product Type | Antibodies Primary |
| Protocol | ELISA: 1/10000; WB: 1/500 - 1/2000 |
| Size | 100µl |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C -20°C for long term storage |
| Substrate / Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Technical Specifications | ELISA: 1/10000; WB: 1/500 - 1/2000 |
| Product Page Updated | 2024-01-25T14:27:22.065Z |
