Article No
AMB-HL4DN1-100
PTEN Primary Antibody
PTEN Primary Antibody
Antibodies Primary
Specifications
| MW | 54kDa |
| Application | WB, ELISA, FC, ICC |
| Article No | AMB-HL4DN1-100 |
| Biosite Brand | Biosite mAb |
| Country Availability | all |
| Clone | 1B8 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | PTEN Primary Antibody |
| Supplier | Nordic Biosite |
| Entrez Gene ID | 5728 |
| Format | Ascitic fluid containing 0.03% sodium azide. |
| Immunogen | Purified recombinant fragment of PTEN expressed in E. Coli. |
| Isotype | IgG1 |
| Notes | PTEN (phosphatase and tensin homolog) was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. This protein is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway. |
| Alias Names | BZS; MHAM; TEP1; PTEN1 |
| Previous Article No | AMB-8414 |
| Product Type | Antibodies Primary |
| Protocol | ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400 |
| Size | 100µl |
| Source / Host | mouse |
| Species Reactivity | human, mouse |
| Storage | 4°C -20°C for long term storage |
| Substrate / Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Technical Specifications | ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400 |
| Product Page Updated | 2024-01-25T14:27:22.065Z |
