WNT1

Article No AMB-8399
Product Type Antibodies Primary
Application ELISA, WB, IHC, ICC, FC
Size 100μl

Specifications

MW 41kDa
Country Availability all
BioSite Brand BioSite mAb
Clone 10C8;
Clone Type monoclonal
Description Mouse Monoclonal Antibody to WNT1
Supplier BioSite Mab
Entrez Gene ID 7471
Immunogen Purified recombinant fragment of WNT1 expressed in E. Coli.
Isotype IgG1
Notes WNT1: wingless-type MMTV integration site family, member 1. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant rolein Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region.
Alias Names INT1
Protocol ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400
Source / Host mouse
Species Reactivity human, mouse
Storage 4 C, -20 C for long term storage
Substrate / Buffer Ascitic fluid containing 0.03% sodium azide.
Technical Specifications ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400
Product Page Updated 2018-10-15T09:15:17.802Z

Shipping info

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Source/Host:

mouse mouse

Species reactivity:

human, mouse human mouse

Suggested protocols:

Western Blot

Western Blot

IHC-P

IHC-P