Article No
AMB-M3SLDV-100
NT5E Primary Antibody
NT5E Primary Antibody
Antibodies Primary
Specifications
| MW | 70kDa |
| Application | ELISA |
| Article No | AMB-M3SLDV-100 |
| Biosite Brand | Biosite mAb |
| Country Availability | all |
| Clone | 1D7 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | NT5E Primary Antibody |
| Supplier | Nordic Biosite |
| Entrez Gene ID | 4907 |
| Format | Ascitic fluid containing 0.03% sodium azide. |
| Immunogen | Purified recombinant fragment of NT5E expressed in E. Coli. |
| Isotype | IgG1 |
| Notes | 5'-nucleotidase, ecto (NT5E), also known as CD73 (Cluster of Differentiation 73). Ecto-5-prime-nucleotidase (5-prime-ribonucleotide phosphohydrolase; EC 3.1.3.5) catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP. The enzyme consists of a dimer of 2 identical 70-kD subunits bound by a glycosyl phosphatidyl inositol linkage to the external face of the plasma membrane. The enzyme is used as a marker of lymphocyte differentiation. Consequently, a deficiency of NT5 occurs in a variety of immunodeficiency diseases (e.g., see MIM 102700, MIM 300300). Other forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from ecto-NT5 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate. |
| Alias Names | eN; NT5; CD73 |
| Previous Article No | AMB-8392 |
| Product Type | Antibodies Primary |
| Protocol | ELISA: 1/10000; IHC: 1/200 - 1/1000 |
| Size | 100µl |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C -20°C for long term storage |
| Substrate / Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Technical Specifications | ELISA: 1/10000; IHC: 1/200 - 1/1000 |
| Product Page Updated | 2024-01-25T14:27:22.065Z |
