CD18

Article No AMB-8372
Product Type Antibodies Primary
Application ELISA, ICC
Size 100μl

Specifications

MW 85kDa
Country Availability all
BioSite Brand BioSite mAb
Clone 10E12;
Clone Type monoclonal
Description Mouse Monoclonal Antibody to CD18
Supplier BioSite Mab
Entrez Gene ID 3689
Immunogen Purified recombinant fragment of CD18 expressed in E. Coli.
Isotype IgG2b
Notes CD18, also known as ITGB2 (integrin beta chain beta 2). Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. CD18 is expressed by most leucocytes. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene.
Alias Names LAD; MF17; LCAMB; LFA-1; ITGB2
Protocol ELISA: 1/10000; ICC: 1/200 - 1/1000
Source / Host mouse
Species Reactivity human, mouse
Storage 4 C, -20 C for long term storage
Substrate / Buffer Ascitic fluid containing 0.03% sodium azide.
Technical Specifications ELISA: 1/10000; ICC: 1/200 - 1/1000
Product Page Updated 2018-10-15T09:15:17.802Z

Shipping info

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Source/Host:

mouse mouse

Species reactivity:

human, mouse human mouse