Article No
AMB-VASLXX-100
FGR Primary Antibody
FGR Primary Antibody
Antibodies Primary
Specifications
| MW | 56kDa |
| Application | WB, ELISA |
| Article No | AMB-VASLXX-100 |
| Biosite Brand | Biosite mAb |
| Country Availability | all |
| Clone | 6G2 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | FGR Primary Antibody |
| Supplier | Nordic Biosite |
| Entrez Gene ID | 2268 |
| Format | Ascitic fluid containing 0.03% sodium azide. |
| Immunogen | Purified recombinant fragment of human FGR expressed in E. Coli. |
| Isotype | IgG1 |
| Notes | FGR: Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog, also known as SRC2; c-fgr; c-src2; FLJ43153; MGC75096; p55c-fgr; p58c-fgr. It is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
| Alias Names | SRC2; c-fgr; c-src2; p55c-fgr; p58c-fgr |
| Previous Article No | AMB-8345 |
| Product Type | Antibodies Primary |
| Protocol | ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000 |
| Size | 100µl |
| Source / Host | mouse |
| Species Reactivity | human, mouse |
| Storage | 4°C -20°C for long term storage |
| Substrate / Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Technical Specifications | ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000 |
| Product Page Updated | 2024-01-25T14:27:22.065Z |
