Article No
AMB-HEXRMS-100
Application | WB, ELISA |
Article No | AMB-HEXRMS-100 |
Biosite Brand | Biosite mAb |
Country Availability | all |
Clone | 3A10H7 |
Clone Type | monoclonal |
Conjugation | Unconjugated |
Description | MSH6 Primary Antibody |
Supplier | Nordic Biosite |
Entrez Gene ID | 2956 |
Format | Ascitic fluid containing 0.03% sodium azide. |
Immunogen | Purified recombinant fragment of MSH6 expressed in E. Coli. |
Isotype | IgG1 |
Notes | Defects in MSH6 are a cause of hereditary non-polyposis colorectal cancer (HNPCC) (Lynch syndrome). HNPCC is an autosomal, dominantly inherited disease associated with marked increase in cancer susceptibility. It is characterized by a familial predisposition to early onset colorectal carcinoma (crc) and extra-colonic cancers of the gastrointestinal, urological and female reproductive tracts. HNPCC is reported to be the most common form of inherited colorectal cancer in the western world. MSH6 is central to mismatch DNA repair. |
Alias Names | GTBP; HSAP; HNPCC5 |
Previous Article No | AMB-8247 |
Product Type | Antibodies Primary |
Protocol | ELISA: 1/10000; WB: 1/500 - 1/2000 |
Size | 100µl |
Source / Host | mouse |
Species Reactivity | human |
Storage | 4°C -20°C for long term storage |
Substrate / Buffer | Ascitic fluid containing 0.03% sodium azide. |
Technical Specifications | ELISA: 1/10000; WB: 1/500 - 1/2000 |
Product Page Updated | 2024-01-25T14:27:22.065Z |