Article No
AMB-P4XDU9-100
TNF-alpha Primary Antibody
TNF-alpha Primary Antibody
Antibodies Primary
Specifications
| Application | WB, ELISA |
| Article No | AMB-P4XDU9-100 |
| Biosite Brand | Biosite mAb |
| Country Availability | all |
| Clone | 2A9B9 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | TNF-alpha Primary Antibody |
| Supplier | Nordic Biosite |
| Entrez Gene ID | 7124 |
| Format | Ascitic fluid containing 0.03% sodium azide. |
| Immunogen | Recombinant Human TNF-alpha (BioSource company, Cat.No. PHC3013) |
| Isotype | IgG1 |
| Notes | TNF-alpha (tumor necrosis factor alpha) is an important cytokine produced by numerous cell types including neutrophils, activated lymphocytes, macrophages and NK cells. It plays a critical role in inflammatory responses and in apoptosis. TNF-alpha is believed to mediate pathogenic shock and tissue injury associated with endotoxemia. TNF-alpha exists as a multimer of two, three, or five non covalently linked units, but shows a single 17 kDa band following SDS PAGE under non reducing conditions. Although it has little effect on many cultured normal human cells, TNF-alpha appears to be directly toxic to vascular endothelial cells. Other actions of TNF-alpha include stimulating growth of human fibroblasts and other cell lines, activating polymorphonuclear neutrophils and osteoclasts, and induction of interleukin 1, prostaglandin E2 and collagenase production. TNF-alpha is currently being evaluated in treatment of certain cancers and AIDS Related Complex. |
| Alias Names | DIF; TNFA; TNFSF2; TNF-alpha |
| Previous Article No | AMB-8220 |
| Product Type | Antibodies Primary |
| Protocol | ELISA: 1/10000; WB: 1/500 - 1/2000 |
| Size | 100µl |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C -20°C for long term storage |
| Substrate / Buffer | Purified antibody in PBS containing 0.03% sodium azide. |
| Technical Specifications | ELISA: 1/10000; WB: 1/500 - 1/2000 |
| Product Page Updated | 2024-01-25T14:27:22.065Z |
