Antibodies Primary

SRA

NEW
Mouse Monoclonal Antibody to SRA

Article No

AMB-8144

Application

ELISA, WB, IHC

Species Reactivity

human

Size

100µl

Clone

7H1G1;

Source / Host

mouse

Suggested protocols

Specifications

Application ELISA, WB, IHC
Article No AMB-8144
BioSite Brand BioSite mAb
Clone 7H1G1;
Clone Type monoclonal
Description Mouse Monoclonal Antibody to SRA
Supplier BioSite Mab
Entrez Gene ID 10011
Immunogen Purified recombinant fragment of SRA expressed in E. Coli.
Isotype IgG1
Notes Steroid receptor RNA activator 1 (SRA), with 237-amino acid protein (about 27kDa), belongs to the growing family of functional non-coding RNAs. SRA was originally described as the first functional noncoding RNA able to specifically coactivate the activity of steroid receptors. Specifically, SRA exists as both an RNA transcript that forms a complex with steroid receptor coactivator-1 and as a stably expressed protein. Its expression is strongly up-regulated in many human tumors of the breast, uterus, and ovary, suggesting a potential role in pathogenesis. Although coactivation of steroid-dependent transcription by SRA is accompanied by a proliferative response, overexpression is not in itself sufficient to induce turmorigenesis.
Alias Names SRAP; STRAA1
Product Type Antibodies Primary
Protocol ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000
Size 100µl
Source / Host mouse
Species Reactivity human
Storage 4°C -20°C for long term storage
Substrate / Buffer Ascitic fluid containing 0.03% sodium azide.
Technical Specifications ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000
Product Page Updated 2019-08-02T12:49:54.081Z

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