Antibodies Primary

ER-alpha

NEW
Mouse Monoclonal Antibody to ER-alpha

Article No

AMB-8126

Application

ELISA, WB, IHC

Species Reactivity

human

Size

100µl

Clone

2B7;

Source / Host

mouse

Suggested protocols

Specifications

Application ELISA, WB, IHC
Article No AMB-8126
BioSite Brand BioSite mAb
Clone 2B7;
Clone Type monoclonal
Description Mouse Monoclonal Antibody to ER-alpha
Supplier BioSite Mab
Entrez Gene ID 2099
Immunogen Purified recombinant fragment of human ER-alpha (410-592aa) expressed in E. Coli.
Isotype IgG1
Notes The estrogen receptor (ER) is a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. Alternative splicing results in several ER mRNA transcripts, which differ primarily in their 5-prime untranslated regions. Two isoforms of the human ER, ERA and ER-beta, occur, each with distinct tissue and cell patterns of expression. Pelletier and El-Alfy (2000) studied the immunocytochemical localization of ESRA and ESRB in human reproductive tissues. In the ovary, ERB immunoreactivity was found in nuclei of granulosa cells of growing follicles at all stages from primary to mature follicles, interstitial gland, and germinal epithelium cells. Nuclear staining for ERA occurred in thecal, interstitial gland, and germinal epithelium cells. In the uterus, strong ERA immunoreactivity was detected in nuclei of epithelial, stromal, and muscle cells.
Alias Names ER; ESR1; Era; ESRA
Product Type Antibodies Primary
Protocol ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000
Size 100µl
Source / Host mouse
Species Reactivity human
Storage 4°C -20°C for long term storage
Substrate / Buffer Purified antibody in PBS containing 0.03% sodium azide.
Technical Specifications ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000
Product Page Updated 2019-08-02T12:49:54.081Z

Shipping info

The delivery time for this item is approximately 5-8 business days. If other deviations occur, this will be noted on the order confirmation or communicated via email. Please note, we do reserve the right to select the best packaging and shipping method in order to insure the stability of the product and allow efficient order tracking.