Article No
AMB-WTZDL1-100
MCL-1 Primary Antibody
MCL-1 Primary Antibody
Antibodies Primary
Specifications
| MW | 37kDa |
| Application | WB, ELISA, ICC |
| Article No | AMB-WTZDL1-100 |
| Biosite Brand | Biosite mAb |
| Country Availability | all |
| Clone | 8C6D4B1 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | MCL-1 Primary Antibody |
| Supplier | Nordic Biosite |
| Entrez Gene ID | 4170 |
| Format | Purified antibody in PBS containing 0.03% sodium azide. |
| Immunogen | Purified recombinant fragment of human MCL-1 expressed in E. Coli. |
| Isotype | IgG1 |
| Notes | Mcl-1 (Myeloid cell leukemia-1) is Bcl-2-related and was identified as an early-induction gene thatincreased in expression during the differentiation of human myeloblastic leukemia cell ML-1, or exposure to different DNA damaging agents. The level of Mcl-1 is decreased in peripheral B lymphocytes undergoing apoptosis following treatment with apoptotic stimuli such as TGF-alpha 1 and forskolin. Expression of Mcl-1 is able to delay apoptosis induced by over-expression of c-myc in CHO 5AHSmyc cells. In hematopoietic FDC-P1 cells, Mcl-1 interacts with another Bcl-2-related protein, Bax, and prolongs cell viability after treatment with different apoptotic reagents.This monoclonal antibody detected a 37kd MCL1 in BCBL-1 cell lysate. |
| Alias Names | EAT, MCL1L, MCL1S |
| Previous Article No | AMB-8113 |
| Product Type | Antibodies Primary |
| Protocol | ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000 |
| Size | 100µl |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C -20°C for long term storage |
| Substrate / Buffer | Purified antibody in PBS containing 0.03% sodium azide. |
| Technical Specifications | ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000 |
| Product Page Updated | 2024-01-25T14:27:22.065Z |
