IL-10

Article No AMB-8097
Product Type Antibodies Primary
Application ELISA, WB
Size 100┬Ál

Specifications

Country Availability all
BioSite Brand BioSite mAb
Clone 3C12C12;
Clone Type monoclonal
Description Mouse Monoclonal Antibody to IL-10
Supplier BioSite Mab
Entrez Gene ID 3586
Immunogen Purified recombinant fragment of human IL-10 expressed in E. Coli.
Isotype IgG1
Notes Interleukine 10 (IL-10) is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down- regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.
Alias Names IL10
Protocol ELISA: 1/10000; WB: 1/500 - 1/2000
Source / Host mouse
Species Reactivity human
Storage 4 C, -20 C for long term storage
Substrate / Buffer Purified antibody in PBS containing 0.03% sodium azide.
Technical Specifications ELISA: 1/10000; WB: 1/500 - 1/2000
Product Page Updated 2018-10-15T09:15:17.802Z

Shipping info

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Source/Host:

mouse mouse

Species reactivity:

human human

Suggested protocols:

Western Blot

Western Blot