Apoa5 (ab)

Article No AMB-8092
Product Type Antibodies Primary
Application ELISA, WB
Size 100µl

Specifications

Country Availability all
BioSite Brand BioSite mAb
Clone 1G5G9(c);
Clone Type monoclonal
Description Mouse Monoclonal Antibody to Apoa5 (ab)
Supplier BioSite Mab
Entrez Gene ID 116519
Immunogen Purified recombinant fragment of human APOA5 (AA: 20-363) expressed in E. Coli.
Isotype IgG1
Notes Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglycerides, whereas a knock-in model with human ApoA5 produced 50–70% lower ; concentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor-_ agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Recently, it was demonstrated that ApoA5 is present in human serum detected by polyclonal antibodies against both the NH2 and COOH termini, although at much lower concentration than other apolipoproteins.
Alias Names RAP3; APOAV; APOA-V
Protocol ELISA: 1/10000; WB: 1/500 - 1/2000
Source / Host mouse
Species Reactivity human
Storage 4 C, -20 C for long term storage
Substrate / Buffer Purified antibody in PBS containing 0.03% sodium azide.
Technical Specifications ELISA: 1/10000; WB: 1/500 - 1/2000
Product Page Updated 2018-10-15T09:15:17.802Z

Shipping info

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Source/Host:

mouse mouse

Species reactivity:

human human

Suggested protocols:

Western Blot

Western Blot