PTPRM

Article No AMB-22312F
Product Type Antibodies Primary
Application ELISA, WB, ICC
Size 0.1mg

Specifications

MW 163.7kDa
Country Availability all
BioSite Brand BioSite mAb
Clone 1H6D10
Clone Type monoclonal
Description PTPRM
Supplier BioSite Mab
Entrez Gene ID 5797
Immunogen Purified recombinant fragment of human PTPRM (AA: extra 565-742) expressed in E. Coli.
Isotype IgG1
Notes The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms.
Alias Names RPTPM; RPTPU; PTPRL1; hR-PTPu; R-PTP-MU
Protocol ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: N/A; FCM: 1/200 - 1/400; IHC: N/A
Species Reactivity human
Storage 4 C, -20 C for long term storage
Substrate / Buffer Purified antibody in PBS with 0.05% sodium azide
Technical Specifications ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: N/A; FCM: N/A; IHC: N/A
Product Page Updated 2018-10-15T09:15:17.802Z

Shipping info

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Species reactivity:

human human

Suggested protocols:

Western Blot

Western Blot