Article No
AM8634b
Specifications
| MW | 74139 |
| Accession Number | P02545 |
| Application | WB |
| Article No | AM8634b |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | 1073CT3.1.3 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | LMNA Antibody |
| Recommended Dilution | 1:4000 |
| Supplier | Abgent |
| Entrez Gene ID | 4000 |
| Format | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
| Isotype | IgG1 k |
| Keywords | Crown Antibodies;Primary Antibodies;Cell Biology;Developmental Biology;Signal Transduction |
| Notes | Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Required for normal development of peripheral nervous system and skeletal muscle and for muscle satellite cell proliferation. Required for osteoblastogenesis and bone formation. Also prevents fat infiltration of muscle and bone marrow, helping to maintain the volume and strength of skeletal muscle and bone. |
| Alias Names | Prelamin-A/C, Lamin-A/C, 70 kDa lamin, Renal carcinoma antigen NY-REN-32, LMNA, LMN1 |
| Product Type | Antibodies Primary |
| Research area | Cell Proliferation |
| Size | 200 µl |
| Source / Host | mouse |
| Species Reactivity | human, mouse, rat |
| Substrate / Buffer | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
| Technical Specifications | This antibody is generated from a mouse immunized with a recombinant protein. |
| Product Page Updated | 2023-11-23T14:38:54.086Z |
