Article No
AM8570b
Specifications
| MW | 125216 |
| Accession Number | Q9NZJ5 |
| Application | WB |
| Article No | AM8570b |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | 1385CT582.4.39 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | EIF2AK3 Antibody |
| Recommended Dilution | 1:250-1:1000 |
| Supplier | Abgent |
| Entrez Gene ID | 9451 |
| Format | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
| Isotype | IgG1 |
| Keywords | Primary Antibodies;Metabolism |
| Notes | Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin-D1 (CCND1). Involved in control of mitochondrial morphology and function (By similarity). |
| Alias Names | Eukaryotic translation initiation factor 2-alpha kinase 3, 2.7.11.1, PRKR-like endoplasmic reticulum kinase, Pancreatic eIF2-alpha kinase, HsPEK, EIF2AK3, PEK, PERK |
| Product Type | Antibodies Primary |
| Research area | Metabolism |
| Size | 200 µl |
| Source / Host | mouse |
| Species Reactivity | human, mouse, rat |
| Substrate / Buffer | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
| Technical Specifications | This EIF2AK3 antibody is generated from a mouse immunized with a recombinant protein conjugated synthetic peptide between 530-850 amino acids from human EIF2AK3. |
| Product Page Updated | 2023-11-23T14:38:54.086Z |
