Article No
AM2226a
VRK1 Antibody
VRK1 Antibody (Center)(Ascites)
Antibodies Primary
Specifications
| MW | 45476 |
| NCBI Number | NP_003375.1 |
| Accession Number | Q99986 |
| Application | WB |
| Article No | AM2226a |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | 1015CT2.1.1 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | VRK1 Antibody (Center)(Ascites) |
| Recommended Dilution | 1:5000 |
| Supplier | Abgent |
| Entrez Gene ID | 7443 |
| Format | Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
| Isotype | IgG1 |
| Keywords | Crown Antibodies;Primary Antibodies;Cell Biology;Signal Transduction |
| Notes | Serine/threonine kinase involved in Golgi disassembly during the cell cycle: following phosphorylation by PLK3 during mitosis, required to induce Golgi fragmentation. Acts by mediating phosphorylation of downstream target protein. Phosphorylates 'Thr-18' of p53/TP53 and may thereby prevent the interaction between p53/TP53 and MDM2. Phosphorylates casein and histone H3. Phosphorylates BANF1: disrupts its ability to bind DNA, reduces its binding to LEM domain-containing proteins and causes its relocalization from the nucleus to the cytoplasm. |
| Alias Names | Serine/threonine-protein kinase VRK1, Vaccinia-related kinase 1, VRK1 |
| Product Type | Antibodies Primary |
| Research area | Cell Proliferation |
| Size | 100 µl |
| Source / Host | mouse |
| Species Reactivity | human |
| Substrate / Buffer | Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
| Technical Specifications | Purified His-tagged VRK1 protein was used to produced this monoclonal antibody. |
| Product Page Updated | 2023-11-23T14:38:54.086Z |
