Article No
AM2205b-ev
Specifications
| MW | 35609 |
| NCBI Number | NP_065390.1 |
| Accession Number | P25963 |
| Application | WB |
| Article No | AM2205b-ev |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | 1121CT8.6.1 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | NFKBIA Antibody |
| Recommended Dilution | 1:1000 |
| Supplier | Abgent |
| Entrez Gene ID | 4792 |
| Format | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
| Isotype | IgG1 k |
| Keywords | Crown Antibodies;Primary Antibodies;Cancer;Cell Biology;Immunology;Signal Transduction |
| Notes | Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription. |
| Alias Names | NF-kappa-B inhibitor alpha, I-kappa-B-alpha, IkB-alpha, IkappaBalpha, Major histocompatibility complex enhancer-binding protein MAD3, NFKBIA, IKBA, MAD3, NFKBI |
| Product Type | Antibodies Primary |
| Size | 80 µl |
| Source / Host | mouse |
| Species Reactivity | human |
| Substrate / Buffer | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
| Technical Specifications | Purified His-tagged NFKBIA protein was used to produced this monoclonal antibody. |
| Product Page Updated | 2023-11-23T14:38:54.086Z |
