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Aranorosin

Chemicals & Biochemicals

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Article No

AG-CN2-0114-M001

Size

1 mg

Shipping Information

Article No

AG-CN2-0114-M001

Size

1 mg

Specifications

CAS No	117184-53-9
MW	419.5
Article No	AG-CN2-0114-M001
Country Availability	SE, FI, DK, NO, IS, EE, LV, LT
Description	Aranorosin
Supplier	Adipogen Life Sciences
Format	Powder
Notes	Antibiotic [1, 2]. Antibacterial [1-6]. Antifungal [1-6]. Anticancer compound [3, 4]. Inhibits anti-apoptotic functions regulated by Bcl-2 [7]. Circumvents arbekacin (ABK)-resistance in MRSA by inhibiting the bifunctional enzyme AAC(6')/APH(2'') [8].\|Chemical. CAS: 117184-53-9. Formula: C23H33NO6. MW: 419.5. Isolated from Gymnascella sp. Antibiotic. Antibacterial. Antifungal. Anticancer compound. Inhibits anti-apoptotic functions regulated by Bcl-2. Circumvents arbekacin (ABK)-resistance in MRSA by inhibiting the bifunctional enzyme AAC(6')/APH(2'').
Molecular Formula	C23H33NO6
Product Type	Chemicals & Biochemicals
Purity	>95%
Research area	Cell Death
Shipping Information	RT
Size	1 mg
Solubility	Soluble in DMSO, ethanol or methanol.
Stability	Stable for at least 3 years after receipt when stored at -20°C.
Storage	-20°C, 4°C
Technical Specifications	Chemical. CAS: 117184-53-9. Formula: C23H33NO6. MW: 419.5. Isolated from Gymnascella sp. Antibiotic. Antibacterial. Antifungal. Anticancer compound. Inhibits anti-apoptotic functions regulated by Bcl-2. Circumvents arbekacin (ABK)-resistance in MRSA by inhibiting the bifunctional enzyme AAC(6')/APH(2'').
Product Page Updated	2024-02-01T08:25:01.492Z

Documentation

Datasheet

MSDS

References

Aranorosin, a novel antibiotic from Pseudoarachniotus roseus. I. Taxonomy, fermentation, isolation, chemical and biological properties: K. Roy, et al.; J. Antibiot. (Tokyo) 41, 1780 (1988) | Aranorosin, a novel antibiotic from Pseudoarachniotus roseus. II. Structure elucidation: H.W. Fehlhaber, et al.; J. Antibiot. (Tokyo) 41, 1785 (1988) | Structure of aranorosin, a new antibiotic of a novel skeletal type: H.W. Fehlhaber, et al.; JACS 110, 8242 (1988) | Stereoselective synthesis of the functionalized spirocyclic core of aranorosin: P. Wipf & Y. Kim; J. Org. Chem. 58, 1649 (1993) | Structure of a model for the aranorosin nucleus: R. C. Haltiwanger, et al.; Acta Cryst. C 50, 274 (1994) | Structure-activity relationships of new aranorosin analogs to antifungal activity: E.K. Vijayakumar, et al.; J. Antibiot. (Tokyo) 51, 522 (1998) | Aranorosin and a novel derivative inhibit the anti-apoptotic functions regulated by Bcl-2: T. Nakashima, et al.; BBRC 377, 1085 (2008) | Aranorosin circumvents arbekacin-resistance in MRSA by inhibiting the bifunctional enzyme AAC(6')/APH(2''): T. Suga, et al.; J. Antibiot. (Tokyo) 65, 527 (2012)

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