Article No
AG-CN2-0103-MM25
Specifications
| CAS No | 29066-42-0 |
| MW | 324.4 |
| Article No | AG-CN2-0103-MM25 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Description | (R,R)-Hymeglusin |
| Supplier | Adipogen Life Sciences |
| Format | Powder |
| Notes | beta-Lactone antibiotic [1]. Antibacterial and antifungal [1, 4]. Specific and irreversible inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase in vitro and in vivo by covalently modifying the active Cys129 residue of the enzyme [2-4, 6-8]. Mevalonate biosynthesis inhibitor [5].|Chemical. CAS: 29066-42-0. Formula: C18H28O5. MW: 324.4. Isolated from fungal strain Scopulariopsis sp. F-244. beta-Lactone antibiotic. Antibacterial and antifungal. Specific and irreversible inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase in vitro and in vivo by covalently modifying the active Cys129 residue of the enzyme. Mevalonate biosynthesis inhibitor. |
| Molecular Formula | C18H28O5 |
| Alias Names | 1233A; F-244; L-659-699 |
| Product Type | Chemicals & Biochemicals |
| Purity | >95% |
| Research area | Metabolism |
| Shipping Information | RT |
| Size | 2.5 mg |
| Solubility | Soluble in methanol, ethanol, DMSO, chloroform or ethyl acetate. Insoluble in water or hexane. |
| Stability | Stable for at least 3 years after receipt when stored at -20°C. |
| Storage | -20°C, 4°C |
| Technical Specifications | Chemical. CAS: 29066-42-0. Formula: C18H28O5. MW: 324.4. Isolated from fungal strain Scopulariopsis sp. F-244. beta-Lactone antibiotic. Antibacterial and antifungal. Specific and irreversible inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase in vitro and in vivo by covalently modifying the active Cys129 residue of the enzyme. Mevalonate biosynthesis inhibitor. |
| Product Page Updated | 2024-02-01T08:25:01.492Z |
