16-epi-Latrunculin B

Article No AG-CN2-0034-C100
Product Type Chemicals & Biochemicals
Research Area Inflammation
Format Powder
Size 100 µg

This product is not available for sale in your country. Please feel free to contact the help desk if you have any questions.

Specifications

CAS No 444911-05-1
MW 395.5
Country Availability DK, EE, FI, IS, LT, LV, NO, SE
Data Sheet Link https://www.adipogen.com/productmanagement/resource/download/type/sheet/id/12231
Description 16-epi-Latrunculin B
Supplier Adipogen Life Sciences
Notes Chemical. CAS: 444911-05-1. Formula: C20H29NO5S. MW: 395.5. Isolated from marine sponge Negombata magnifica. Antiviral (against herpes simplex type 1 virus (HSV-1)). Cytotoxic. Depolymerizes actin filaments (F-actin).
Molecular Formula C20H29NO5S
Purity >98% (HPLC)
References Toward computing relative configurations: 16-epi-latrunculin B, a new stereoisomer of the actin polymerization inhibitor latrunculin B: T.R. Hoye, et al.; JACS 124, 7405 (2002) Abstract | A new dimension to the biosynthetic products isolated from the sponge Negombata magnifica: B. Vilozny, et al.; J. Nat. Prod. 67, 1055 (2004) | Diverted total synthesis: Preparation of a focused library of latrunculin analogues and evaluation of their actin-binding properties: A. Fürstner, et al.; PNAS 102, 8103 (2005) | Total syntheses of the actin-binding macrolides latrunculin A, B, C, M, S and 16-epi-latrunculin B: A. Fürstner, et al.; Chemistry 13, 115 (2007) | Interrogating the Bioactive Pharmacophore of the Latrunculin Chemotype by Investigating the Metabolites of Two Taxonomically Unrelated Sponges: T. Amagata, et al.; J. Med. Chem. 51, 7234 (2008)
Solubility Soluble in DMSO or ethanol.
Source / Host fungi
Storage -20°C
Technical Specifications Antiviral (against herpes simplex type 1 virus (HSV-1)). Cytotoxic. Depolymerizes actin filaments (F-actin).

Shipping info

The delivery time for this item is approximately 5-8 business days. If other deviations occur, this will be noted on the order confirmation or communicated via email. Please note, we do reserve the right to select the best packaging and shipping method in order to insure the stability of the product and allow efficient order tracking.

Source/Host:

fungi

Product insert:

Product data sheet

Datasheet