LysoGlow84

LysoGlow84

Chemicals & Biochemicals

Article No

AG-CMA-1005-M001

Size

1 mg

Shipping Information

RT

Article No

AG-CMA-1005-M001

Size

1 mg

Shipping Information

RT

Specifications

CAS No 1782983-52-1
MW 246.3 . 113.0
Additional Information Fluorescence/Spectral properties: Excitation 310 - 380nm; maximum at ~320nm Emission 400 - 520nm; maximum at 440nm (pH3 to pH6) and 400nm (pH 8 to pH 13) Prepare a 10mM stock solution in MeOH or DMSO:Dissolve 1mg of LysoGlow84 in 278µl methanol, mix gently until the compound is completely dissolved. The solution should show a homogenous yellow color. Use fresh preparations or aliquot and freeze immediately. LysoGlow84 is light sensitive, avoid long exposure to direct light or other bright light sources. Avoid freeze/thaw cycles of solutions.
Article No AG-CMA-1005-M001
Country Availability SE, FI, DK, NO, IS, EE, LV, LT
Description LysoGlow84
Supplier Adipogen Life Sciences
Additional Information Fluorescence/Spectral properties: Excitation 310 - 380nm; maximum at ~320nm Emission 400 - 520nm; maximum at 440nm (pH3 to pH6) and 400nm (pH 8 to pH 13) Prepare a 10mM stock solution in MeOH or DMSO:Dissolve 1mg of LysoGlow84 in 278µl methanol, mix gently until the compound is completely dissolved. The solution should show a homogenous yellow color. Use fresh preparations or aliquot and freeze immediately. LysoGlow84 is light sensitive, avoid long exposure to direct light or other bright light sources. Avoid freeze/thaw cycles of solutions.
Format Powder
Notes Cell/membrane permeable, non-toxic, pH-sensitive fluorescent dye (blue-green range) for live imaging of pH alteration in acidic organelles, lysosomes, autophagolysosomes, vesicles, cells, tissue and even small, transparent whole animals without side effects. Useful as intracellular pH indicator with a wide range of fluorescence (pH 3 to pH 13). pH-dependent dual-emission peaks, can be used for ratiometric evaluation of pH (F400/440). No esterases are involved, therefore no toxic by-products occur. Long-term stable; is barely metabolized. Fluorescence co-localizes with LysoTracker® Red DND-99. (LysoTracker® is a registered trademark of Molecular Probes, Inc.)|Chemical. CAS: 1782983-52-1. Formula: C16H12N3 . C2F3O2. MW: 246.3 . 113.0. Synthetic. Cell/membrane permeable, non-toxic, pH-sensitive fluorescent dye (blue-green range) for live imaging of pH alteration in acidic organelles, lysosomes, autophagolysosomes, vesicles, cells, tissue and even small, transparent whole animals without side effects. Useful as intracellular pH indicator with a wide range of fluorescence (pH 3 to pH 13). pH-dependent dual-emission peaks, can be used for ratiometric evaluation of pH (F400/440). No esterases are involved, therefore no toxic by-products occur. Long-term stable; is barely metabolized. Fluorescence co-localizes with LysoTracker® Red DND-99. (LysoTracker® is a registered trademark of Molecular Probes, Inc.)
Molecular Formula C16H12N3 . C2F3O2
Alias Names 4-(Naphthalene-2-yl)-1H-imidazo[4,5-c]pyridine . TFA
Product Type Chemicals & Biochemicals
Protocol Fluorescence/Spectral properties: Excitation 310 - 380nm; maximum at ~320nm Emission 400 - 520nm; maximum at 440nm (pH3 to pH6) and 400nm (pH 8 to pH 13) Prepare a 10mM stock solution in MeOH or DMSO:Dissolve 1mg of LysoGlow84 in 278µl methanol, mix gently until the compound is completely dissolved. The solution should show a homogenous yellow color. Use fresh preparations or aliquot and freeze immediately. LysoGlow84 is light sensitive, avoid long exposure to direct light or other bright light sources. Avoid freeze/thaw cycles of solutions.
Purity >98%
Find out more about our research areas  Biochemical, Immunology, Molecular Biology and Pathology Cell Death
Shipping Information RT
Size 1 mg
Solubility Soluble in DMSO, methanol or other polar solvents. Poorly soluble in water at pH8 to pH12.
Stability Stable for at least 2 years after receipt when stored at -20°C. Stable for at least 1 year after receipt when stored at +4°C. Stock solutions are stable for at least 3 months when stored at -20°C.
Storage -20°C, 4°C
Technical Specifications Chemical. CAS: 1782983-52-1. Formula: C16H12N3 . C2F3O2. MW: 246.3 . 113.0. Synthetic. Cell/membrane permeable, non-toxic, pH-sensitive fluorescent dye (blue-green range) for live imaging of pH alteration in acidic organelles, lysosomes, autophagolysosomes, vesicles, cells, tissue and even small, transparent whole animals without side effects. Useful as intracellular pH indicator with a wide range of fluorescence (pH 3 to pH 13). pH-dependent dual-emission peaks, can be used for ratiometric evaluation of pH (F400/440). No esterases are involved, therefore no toxic by-products occur. Long-term stable; is barely metabolized. Fluorescence co-localizes with LysoTracker® Red DND-99. (LysoTracker® is a registered trademark of Molecular Probes, Inc.)
Product Page Updated 2024-02-01T08:25:01.492Z

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