Article No
AG-40T-0108-C050
NAD Synthetase (M. tuberculosis) (rec.) (His)
NAD Synthetase (M. tuberculosis) (rec.) (His)
Enzymes
Specifications
| MW | ~75.0kDa |
| Article No | AG-40T-0108-C050 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Concentration | 0.5 mg/ml |
| Description | NAD Synthetase (M. tuberculosis) (rec.) (His) |
| Supplier | Adipogen Life Sciences |
| Entrez Gene ID | 885808 |
| Format | Liquid |
| Gene Symbol | nadE |
| Notes | NAD synthetase is an essential enzyme involved in both the de novo biosynthesis and salvage of NAD+, catalyzing the final step of both pathways. Since NAD has a vital role in cell metabolism, the enzyme represents a valid target for the development of new antimycobacterial agents. It can use both glutamine or ammonia as a nitrogen source. Catalytic activity: ATP + deamido-NAD+ + L-glutamine + H2O = AMP + diphosphate + NAD+ + L-glutamate|Protein. NAD synthetase (Mycobacterium tuberculosis) (with mutation S444A) is fused at the N-terminus to a His-tag. Source: E. coli. Endotoxin content: N/A. Liquid. In 20mM TRIS-HCl, pH 7.8. Purity: >98% (SDS-PAGE). NAD synthetase is an essential enzyme involved in both the de novo biosynthesis and salvage of NAD+, catalyzing the final step of both pathways. Since NAD has a vital role in cell metabolism, the enzyme represents a valid target for the development of new antimycobacterial agents. It can use both glutamine or ammonia as a nitrogen source. Catalytic activity: ATP + deamido-NAD+ + L-glutamine + H2O = AMP + diphosphate + NAD+ + L-glutamate |
| Alias Names | NADE; Glutamine-dependent NAD(+) Synthetase; EC 6.3.5.1 |
| Product Type | Enzymes |
| Purity | >98% |
| Research area | Metabolism |
| Sequence | NAD synthetase (Mycobacterium tuberculosis) (with mutation S444A) is fused at the N-terminus to a His-tag. |
| Shipping Information | DRY ICE |
| Size | 50 ug |
| Stability | Stable for at least 6 months after receipt when stored at -80°C. |
| Storage | -20°C, -80°C |
| Substrate / Buffer | Liquid. In 20mM TRIS-HCl, pH 7.8. |
| Technical Specifications | Protein. NAD synthetase (Mycobacterium tuberculosis) (with mutation S444A) is fused at the N-terminus to a His-tag. Source: E. coli. Endotoxin content: N/A. Liquid. In 20mM TRIS-HCl, pH 7.8. Purity: >98% (SDS-PAGE). NAD synthetase is an essential enzyme involved in both the de novo biosynthesis and salvage of NAD+, catalyzing the final step of both pathways. Since NAD has a vital role in cell metabolism, the enzyme represents a valid target for the development of new antimycobacterial agents. It can use both glutamine or ammonia as a nitrogen source. Catalytic activity: ATP + deamido-NAD+ + L-glutamine + H2O = AMP + diphosphate + NAD+ + L-glutamate |
| UniProt Number | P0A5L6 |
| Product Page Updated | 2024-02-01T08:25:01.492Z |
