Article No
AG-40B-0131-3010
Angiopoietin-2 (mouse) (rec.) MultiPack
Angiopoietin-2 (mouse) (rec.) MultiPack
Proteins & Peptides
Specifications
| MW | ~70kDa (SDS-PAGE) |
| Article No | AG-40B-0131-3010 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Concentration | 0.1 mg/ml |
| Description | Angiopoietin-2 (mouse) (rec.) MultiPack |
| Supplier | Adipogen Life Sciences |
| Endotoxin | <0.05EU/µg purified protein (LAL test). |
| Entrez Gene ID | 11601 |
| Format | Powder |
| Gene Symbol | Angpt2 |
| Notes | Angiopoietin-1 (Ang-1) and Angiopoietin-2 (Ang-2) are closely related secreted ligands which bind with similar affinity to Tie-2. Tie-2 and angiopoietins have been shown to play critical roles in embryogenic angiogenesis and in maintaining the integrity of the adult vasculature. Ang-1 activates Tie-2 signaling on endothelial cells to promote chemotaxis, cell survival, cell sprouting, vessel growth and stabilization. Ang-2 has been identified as a secreted protein ligand of Tie-2 and has alternatively been reported to be an antagonist for Ang-1 induced Tie-2 signaling as well as an agonist for Tie-2 signaling, depending on the cell context.|Protein. Mouse angiopoietin-2 (aa 19-496) is fused at the N-terminus to a FLAG®-tag. Source: HEK 293 cells. Endotoxin content: 95% (SDS-PAGE). Angiopoietin-1 (Ang-1) and Angiopoietin-2 (Ang-2) are closely related secreted ligands which bind with similar affinity to Tie-2. Tie-2 and angiopoietins have been shown to play critical roles in embryogenic angiogenesis and in maintaining the integrity of the adult vasculature. Ang-1 activates Tie-2 signaling on endothelial cells to promote chemotaxis, cell survival, cell sprouting, vessel growth and stabilization. Ang-2 has been identified as a secreted protein ligand of Tie-2 and has alternatively been reported to be an antagonist for Ang-1 induced Tie-2 signaling as well as an agonist for Tie-2 signaling, depending on the cell context. |
| Alias Names | Ang-2; Ang2; Angpt2; Agpt2 |
| Product Type | Proteins & Peptides |
| Purity | >95% |
| Research area | Metabolism |
| Sequence | Mouse angiopoietin-2 (aa 19-496) is fused at the N-terminus to a FLAG®-tag. |
| Shipping Information | BLUE ICE |
| Size | 3 x 10 ug |
| Source / Host | mouse |
| Species Reactivity | human, mouse |
| Stability | Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
| Storage | -20°C, 4°C |
| Substrate / Buffer | Lyophilized. Contains PBS with trehalose and Brij35. |
| Technical Specifications | Protein. Mouse angiopoietin-2 (aa 19-496) is fused at the N-terminus to a FLAG®-tag. Source: HEK 293 cells. Endotoxin content: 95% (SDS-PAGE). Angiopoietin-1 (Ang-1) and Angiopoietin-2 (Ang-2) are closely related secreted ligands which bind with similar affinity to Tie-2. Tie-2 and angiopoietins have been shown to play critical roles in embryogenic angiogenesis and in maintaining the integrity of the adult vasculature. Ang-1 activates Tie-2 signaling on endothelial cells to promote chemotaxis, cell survival, cell sprouting, vessel growth and stabilization. Ang-2 has been identified as a secreted protein ligand of Tie-2 and has alternatively been reported to be an antagonist for Ang-1 induced Tie-2 signaling as well as an agonist for Tie-2 signaling, depending on the cell context. |
| UniProt Number | O35608 |
| Product Page Updated | 2024-02-01T08:25:01.492Z |
