Article No
AG-40B-0118-3010
MW | ~47kDa (SDS-PAGE) |
Article No | AG-40B-0118-3010 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
Concentration | 0.1 mg/ml |
Description | PEDF (mouse) (rec.) MultiPack |
Supplier | Adipogen Life Sciences |
Endotoxin | <0.01EU/µg purified protein (LAL test; Lonza). |
Entrez Gene ID | 20317 |
Format | Powder |
Gene Symbol | Serpinf1 |
Notes | Pigment epithelium-derived factor (PEDF) is a 47kDa secreted glycoprotein that belongs to the non-inhibitory serpin family group. PEDF is widely expressed in adult and fetal tissues, including brain, spinal cord, plasma, bone, prostate, pancreas, heart and lung. PEDF acts as an angiogenesis inhibitor with neurotrophic, immunomodulation and antitumor properties. It functions as anti-angiogenic agent by counterbalancing the proangiogenic effect of VEGF. PEDF is one of the most abundant proteins released by adipocytes and induces insulin resistance in adipocytes and human skeletal muscle cells. Recently, it has been reported that PEDF is sufficient to maintain the self-renewal of pluripotent human embryonic stem cells.|Protein. Mouse PEDF (aa 20-417) is fused at the C-terminus to a FLAG®-tag. Source: CHO cells. Endotoxin content: 95% (SDS-PAGE). Pigment epithelium-derived factor (PEDF) is a 47kDa secreted glycoprotein that belongs to the non-inhibitory serpin family group. PEDF is widely expressed in adult and fetal tissues, including brain, spinal cord, plasma, bone, prostate, pancreas, heart and lung. PEDF acts as an angiogenesis inhibitor with neurotrophic, immunomodulation and antitumor properties. It functions as anti-angiogenic agent by counterbalancing the proangiogenic effect of VEGF. PEDF is one of the most abundant proteins released by adipocytes and induces insulin resistance in adipocytes and human skeletal muscle cells. Recently, it has been reported that PEDF is sufficient to maintain the self-renewal of pluripotent human embryonic stem cells. |
Alias Names | Pigment Epithelium-derived Factor; Stromal Cell-derived Factor 3; Serpin F1; Caspin |
Product Type | Proteins & Peptides |
Purity | >95% |
Research area | Metabolism |
Sequence | Mouse PEDF (aa 20-417) is fused at the C-terminus to a FLAG®-tag. |
Shipping Information | BLUE ICE |
Size | 3 x 10 ug |
Source / Host | mouse |
Species Reactivity | mouse |
Stability | Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
Storage | -20°C, 4°C |
Substrate / Buffer | Lyophilized. Contains PBS. |
Technical Specifications | Protein. Mouse PEDF (aa 20-417) is fused at the C-terminus to a FLAG®-tag. Source: CHO cells. Endotoxin content: 95% (SDS-PAGE). Pigment epithelium-derived factor (PEDF) is a 47kDa secreted glycoprotein that belongs to the non-inhibitory serpin family group. PEDF is widely expressed in adult and fetal tissues, including brain, spinal cord, plasma, bone, prostate, pancreas, heart and lung. PEDF acts as an angiogenesis inhibitor with neurotrophic, immunomodulation and antitumor properties. It functions as anti-angiogenic agent by counterbalancing the proangiogenic effect of VEGF. PEDF is one of the most abundant proteins released by adipocytes and induces insulin resistance in adipocytes and human skeletal muscle cells. Recently, it has been reported that PEDF is sufficient to maintain the self-renewal of pluripotent human embryonic stem cells. |
UniProt Number | P97298 |
Product Page Updated | 2024-02-01T08:25:01.492Z |