Article No
AG-40B-0040-3010
Netrin-1 (human) (rec.) MultiPack
Netrin-1 (human) (rec.) MultiPack
Proteins & Peptides
Specifications
| MW | ~80kDa (SDS-PAGE) |
| Article No | AG-40B-0040-3010 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Concentration | 10µg vial: 0.1mg/ml after reconstitution.100µg vial: 1mg/ml after reconstitution. |
| Description | Netrin-1 (human) (rec.) MultiPack |
| Supplier | Adipogen Life Sciences |
| Endotoxin | <0.01EU/µg purified protein (LAL test; Lonza). |
| Entrez Gene ID | 9423 |
| Format | Powder |
| Gene Symbol | NTN1 |
| Notes | Netrin-1 controls guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Netrin-1 is also Involved in tumorigenesis by regulating apoptosis. Netrin-1 promotes atherosclerosis by retaining macrophages in the artery wall. Netrin-1 also governs induced pluripotent stem cell (iPS) formation and improves reprogramming efficiency of human and mouse somatic cells by limiting apoptosis mediated by Netrin-1 receptors DCC or UNC5b.|Protein. Human netrin-1 (aa 25-604) is fused at the C-terminus to a FLAG®-tag. Source: HEK 293 cells. Endotoxin content: 95% (SDS-PAGE). Netrin-1 controls guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Netrin-1 is also Involved in tumorigenesis by regulating apoptosis. Netrin-1 promotes atherosclerosis by retaining macrophages in the artery wall. Netrin-1 also governs induced pluripotent stem cell (iPS) formation and improves reprogramming efficiency of human and mouse somatic cells by limiting apoptosis mediated by Netrin-1 receptors DCC or UNC5b. |
| Alias Names | NTN1 |
| Product Type | Proteins & Peptides |
| Purity | >95% |
| Research area | Inflammation |
| Sequence | Human netrin-1 (aa 25-604) is fused at the C-terminus to a FLAG®-tag. |
| Shipping Information | BLUE ICE |
| Size | 3 x 10 ug |
| Source / Host | human |
| Species Reactivity | human, mouse, rat |
| Stability | Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
| Storage | -20°C, 4°C |
| Substrate / Buffer | Lyophilized. Contains PBS plus protein stabilizer. No BSA included. The protein stabilizer shows no interference with protein activity. |
| Technical Specifications | Protein. Human netrin-1 (aa 25-604) is fused at the C-terminus to a FLAG®-tag. Source: HEK 293 cells. Endotoxin content: 95% (SDS-PAGE). Netrin-1 controls guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Netrin-1 is also Involved in tumorigenesis by regulating apoptosis. Netrin-1 promotes atherosclerosis by retaining macrophages in the artery wall. Netrin-1 also governs induced pluripotent stem cell (iPS) formation and improves reprogramming efficiency of human and mouse somatic cells by limiting apoptosis mediated by Netrin-1 receptors DCC or UNC5b. |
| UniProt Number | O95631 |
| Product Page Updated | 2024-02-01T08:25:01.492Z |
