Article No
AG-40B-0011-3050
DR6 (human):Fc (human) (rec.) MultiPack
DR6 (human):Fc (human) (rec.) MultiPack
Proteins & Peptides
Specifications
| MW | ~80kDa (SDS-PAGE) |
| Article No | AG-40B-0011-3050 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Concentration | 1 mg/ml |
| Description | DR6 (human):Fc (human) (rec.) MultiPack |
| Supplier | Adipogen Life Sciences |
| Endotoxin | <0.1EU/µg purified protein (LAL test; Lonza). |
| Entrez Gene ID | 27242 |
| Format | Powder |
| Gene Symbol | TNFRSF21 |
| Notes | DR6 is an orphan TNF receptor superfamily member belonging to a subgroup of receptors called death receptors. Expressed ubiquitously with high expression in lymphoid organs, heart, brain, and pancreas. Broadly expressed by developing neurons where it functions as pro-apoptotic factor. Recently, it has been reported that interaction with the beta-amyloid precursor protein (APP) activates a widespread caspase-dependent self-destruction program dependent on caspase-6.|Protein. The Fc portion of human IgG1 is fused to the C-terminus of human DR6 (aa 42-351). Source: HEK 293 cells. Endotoxin content: 95% (SDS-PAGE). DR6 is an orphan TNF receptor superfamily member belonging to a subgroup of receptors called death receptors. Expressed ubiquitously with high expression in lymphoid organs, heart, brain, and pancreas. Broadly expressed by developing neurons where it functions as pro-apoptotic factor. Recently, it has been reported that interaction with the beta-amyloid precursor protein (APP) activates a widespread caspase-dependent self-destruction program dependent on caspase-6. |
| Alias Names | Tumor Necrosis Factor Receptor Superfamily Member 21; TNFRSF21; Death Receptor 6; CD358 |
| Product Type | Proteins & Peptides |
| Purity | >95% |
| Research area | Cell Death |
| Sequence | The Fc portion of human IgG1 is fused to the C-terminus of human DR6 (aa 42-351). |
| Shipping Information | BLUE ICE |
| Size | 3 x 50 ug |
| Source / Host | human |
| Species Reactivity | human |
| Stability | Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
| Storage | -20°C, 4°C |
| Substrate / Buffer | Lyophilized. Contains PBS. |
| Technical Specifications | Protein. The Fc portion of human IgG1 is fused to the C-terminus of human DR6 (aa 42-351). Source: HEK 293 cells. Endotoxin content: 95% (SDS-PAGE). DR6 is an orphan TNF receptor superfamily member belonging to a subgroup of receptors called death receptors. Expressed ubiquitously with high expression in lymphoid organs, heart, brain, and pancreas. Broadly expressed by developing neurons where it functions as pro-apoptotic factor. Recently, it has been reported that interaction with the beta-amyloid precursor protein (APP) activates a widespread caspase-dependent self-destruction program dependent on caspase-6. |
| UniProt Number | O75509 |
| Product Page Updated | 2024-02-01T08:25:01.492Z |
