Article No
AG-40A-0112-C010
MW | ~65kDa (SDS-PAGE) |
Article No | AG-40A-0112-C010 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
Concentration | Delete |
Description | FTO (human) (rec.) (His) |
Supplier | Adipogen Life Sciences |
Endotoxin | <1EU/µg purified protein (LAL test; Lonza). |
Entrez Gene ID | 79068 |
Format | Liquid |
Gene Symbol | FTO |
Notes | FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse 'fused toes' mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol.|Protein. Human FTO (aa 2-505) is fused at the N-terminus to a His-tag. Source: E. coli. Endotoxin content: 90% (SDS-PAGE). FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse 'fused toes' mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol. |
Alias Names | Fat Mass and Obesity-associated Protein; FATSO |
Product Type | Proteins & Peptides |
Purity | >90% |
Research Area | Metabolism |
Sequence | Human FTO (aa 2-505) is fused at the N-terminus to a His-tag. |
Shipping Information | BLUE ICE |
Size | 10 ug |
Source / Host | human |
Species Reactivity | human |
Stability | Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
Storage | -20°C, 4°C |
Substrate / Buffer | Liquid. 0.2µm-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl. |
Technical Specifications | Protein. Human FTO (aa 2-505) is fused at the N-terminus to a His-tag. Source: E. coli. Endotoxin content: 90% (SDS-PAGE). FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse ‘fused toes’ mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol. |
UniProt Number | Q9C0B1 |
Product Page Updated | 2024-02-01T08:25:01.492Z |