Article No
AG-25B-0015-C050
anti-PIDD, pAb (AL233)
anti-PIDD, pAb (AL233)
Antibodies Primary
Specifications
| Application | IHC, IP, WB |
| Article No | AG-25B-0015-C050 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | polyclonal |
| Clone Type | polyclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | anti-PIDD, pAb (AL233) |
| Supplier | Adipogen Life Sciences |
| Entrez Gene ID | 55367 |
| Format | Liquid |
| Gene Symbol | PIDD1 |
| Immunogen | Recombinant human PIDD (Death Domain: aa 776-910). |
| Notes | PIDD promotes apoptosis downstream of the tumor suppressor as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. It associates with NEMO/IKBKG and RIP1 and enhances sumoylation and ubiquitination of NEMO/IKBKG which is important for activation of the transcription factor NF-kappa-B. It associates with caspase-2 and RAIDD, and induces activation of caspase-2 which is an important regulator in the apoptotic pathways.|Polyclonal Antibody. Recognizes human and the native form of mouse PIDD. Detects bands of ~90kDa (full length protein) and ~50kDa (cleaved protein) by Western blot. Source: Rabbit. Applications: IHC, IP, WB. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. PIDD promotes apoptosis downstream of the tumor suppressor as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. It associates with NEMO/IKBKG and RIP1 and enhances sumoylation and ubiquitination of NEMO/IKBKG which is important for activation of the transcription factor NF-kappa-B. It associates with caspase-2 and RAIDD, and induces activation of caspase-2 which is an important regulator in the apoptotic pathways. |
| Alias Names | p53-induced Protein with a Death Domain; Leucine-rich Repeat and Death Domain-containing Protein; Lrdd |
| Product Type | Antibodies Primary |
| Research area | Cell Death |
| Shipping Information | BLUE ICE |
| Size | 50 ug |
| Source / Host | rabbit |
| Species Reactivity | human, mouse |
| Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Storage | -20°C, 4°C |
| Substrate / Buffer | Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. |
| Technical Specifications | Polyclonal Antibody. Recognizes human and the native form of mouse PIDD. Detects bands of ~90kDa (full length protein) and ~50kDa (cleaved protein) by Western blot. Source: Rabbit. Applications: IHC, IP, WB. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. PIDD promotes apoptosis downstream of the tumor suppressor as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. It associates with NEMO/IKBKG and RIP1 and enhances sumoylation and ubiquitination of NEMO/IKBKG which is important for activation of the transcription factor NF-kappa-B. It associates with caspase-2 and RAIDD, and induces activation of caspase-2 which is an important regulator in the apoptotic pathways. |
| UniProt Number | Q9HB75 |
| Product Page Updated | 2024-02-01T08:25:01.492Z |
