Article No
AG-20B-0012TM-T100
anti-LAG-3 (human), mAb (17B4) (ATTO 590)
anti-LAG-3 (human), mAb (17B4) (ATTO 590)
Antibodies Primary
Specifications
| Additional Information | New ATTO-fluorescent antibodies show increased photostability, outstanding brightness and intense signals. ATTO dyes are thermally stable, resistant to environmental changes and show no significant isomerization. ATTO 590 shows bright red fluorescence (lambdaabs (max): 594nm, lambdaem (max): 624nm, epsilonmax: 120’000). |
| Application | ICC |
| Article No | AG-20B-0012TM-T100 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | 17B4 |
| Clone Type | monoclonal |
| Concentration | 0.5 mg/ml |
| Conjugation | ATTO 590 |
| Description | anti-LAG-3 (human), mAb (17B4) (ATTO 590) |
| Supplier | Adipogen Life Sciences |
| Entrez Gene ID | 3902 |
| Additional Information | New ATTO-fluorescent antibodies show increased photostability, outstanding brightness and intense signals. ATTO dyes are thermally stable, resistant to environmental changes and show no significant isomerization. ATTO 590 shows bright red fluorescence (lambdaabs (max): 594nm, lambdaem (max): 624nm, epsilonmax: 120'000). |
| Format | Liquid |
| Gene Symbol | LAG3 |
| Immunogen | Synthetic peptide corresponding to 30 aa in the N-terminus of human LAG-3. |
| Isotype | IgG1 k |
| Notes | Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.|Monoclonal Antibody. Recognizes human LAG-3. Isotype: Mouse IgG1. Clone: 17B4. Applications: ICC. Liquid. In PBS containing 0.02% sodium azide. Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4. |
| Alias Names | Lymphocyte Activation Gene-3; FDC Protein; CD223 |
| Product Type | Antibodies Primary |
| Protocol | New ATTO-fluorescent antibodies show increased photostability, outstanding brightness and intense signals. ATTO dyes are thermally stable, resistant to environmental changes and show no significant isomerization. ATTO 590 shows bright red fluorescence (lambdaabs (max): 594nm, lambdaem (max): 624nm, epsilonmax: 120’000). |
| Purity | >95% |
| Research area | Immunology |
| Shipping Information | BLUE ICE |
| Size | 100 tests |
| Source / Host | mouse |
| Species Reactivity | human |
| Stability | Keep conjugated formats at +4°C. Stable for at least 1 year after receipt when stored at +4°C. |
| Storage | 4°C |
| Substrate / Buffer | Liquid. In PBS containing 0.02% sodium azide. |
| Technical Specifications | Monoclonal Antibody. Recognizes human LAG-3. Isotype: Mouse IgG1. Clone: 17B4. Applications: ICC. Liquid. In PBS containing 0.02% sodium azide. Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4. |
| UniProt Number | P18627 |
| Product Page Updated | 2024-02-01T08:25:01.492Z |
