Article No
AG-20B-0012PF-C100
anti-LAG-3 (human), mAb (17B4) (blocking) (preservative free)
anti-LAG-3 (human), mAb (17B4) (blocking) (preservative free)
Antibodies Primary
Specifications
| Application | Block, FC, ICC, IHC, IP, WB |
| Article No | AG-20B-0012PF-C100 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | 17B4 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | anti-LAG-3 (human), mAb (17B4) (blocking) (preservative free) |
| Supplier | Adipogen Life Sciences |
| Endotoxin | <0.001EU/µg purified protein or <1EU/mg purified protein (LAL test; Lonza). |
| Entrez Gene ID | 3902 |
| Format | Liquid |
| Gene Symbol | LAG3 |
| Immunogen | Synthetic peptide corresponding to 30 aa in the N-terminus of human LAG-3. |
| Isotype | IgG1 k |
| Notes | Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.|Monoclonal Antibody. Recognizes human LAG-3. Isotype: Mouse IgG1. Clone: 17B4. Applications: FACS, FUNC (Blocking), ICC, IHC, IP, WB. Liquid. In PBS. Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4. |
| Alias Names | Lymphocyte Activation Gene-3; FDC Protein; CD223 |
| Product Type | Antibodies Primary |
| Purity | >95% |
| Research area | Immunology |
| Shipping Information | BLUE ICE |
| Size | 100 ug |
| Source / Host | mouse |
| Species Reactivity | human |
| Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Storage | -20°C, 4°C |
| Substrate / Buffer | Liquid. In PBS. |
| Technical Specifications | Monoclonal Antibody. Recognizes human LAG-3. Isotype: Mouse IgG1. Clone: 17B4. Applications: FACS, FUNC (Blocking), ICC, IHC, IP, WB. Liquid. In PBS. Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4. |
| UniProt Number | P18627 |
| Product Page Updated | 2024-02-01T08:25:01.492Z |
