NG2 / Chondroitin sulfate proteoglycan 4

Article No AFC-E17EAC
Product Type Antibodies Primary
Application FC, IP, WB, ICC
Size 100 tests

Specifications

Country Availability all
BioSite Brand BioSite Flow
Clone 7.1
Clone Type monoclonal
Conjugation PE
Description Mouse Monoclonal to NG2 / Chondroitin sulfate proteoglycan 4
Recommended Dilution The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
Supplier BioSite Flow
Immunogen Human bone marrow stromal cells infected with SV-40
Isotype IgG1
Keywords CD and Related Antigens (Human)
Notes NG2 / Chondroitin sulfate proteoglycan 4 is expressed on glial cell populations, but not on normal hepatopoietic cells. It is an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells, where it plays role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes, and supports signaling pathways important for tumor invasion and growth. NG2 also serves as an AML blast tumor marker associated with poor prognosis.
Species Reactivity human
Storage Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
Substrate / Buffer The reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 15mM sodium azide.
Technical Specifications The mouse monoclonal antibody 7.1 recognizes NG2, the melanoma-associated chondroitin sulfate proteoglycan 4 of Mw approximately 220-300 kDa.
Product Page Updated 2018-07-27T09:12:01.609Z

Shipping info

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Species reactivity:

human human