CD267 / TACI

Article No AFC-BC3C0E
Product Type Antibodies Primary
Application FC
Size 100 tests

Specifications

Country Availability all
BioSite Brand BioSite Flow
Clone 1A1
Clone Type monoclonal
Conjugation APC
Description Rat Monoclonal to CD267 / TACI
Recommended Dilution The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
Supplier BioSite Flow
Immunogen CD267-transfected RBL cells
Isotype IgG2a
Keywords CD and Related Antigens (Human)
Notes CD267 / TACI (Transmembrane Activator Calcium modulator and cyclophilin ligand Interactor), a TNFR superfamily transmembrane protein, is expressed on B cells (predominantly on CD27+ memory cells), multiple myeloma cells and B cell chronic lymphocytic leukemia (B-CLL). Its triggering leads to activation of the transcription factors NFAT, AP1, and NF-kappa-B. It plays a crucial role in humoral immunity. Mutations in CD267 are associated with common variable immunodeficiency and IgA deficiency.
Species Reactivity human
Storage Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
Substrate / Buffer The reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 15mM sodium azide.
Technical Specifications The rat monoclonal antibody 1A1 recognizes CD267 / TACI, a 32 kDa type III transmembrane protein expressed by B cells and possibly by some activated T cells._x000D_ <br>_x000D_ <b>HLDA 8 Workshop</b>
Product Page Updated 2018-07-27T09:12:01.609Z

Shipping info

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Species reactivity:

human human