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Antibodies Primary

CD15

Mouse Monoclonal to CD15 / Lewis x Blood Group antigen

Make a customized order

Article No

AFC-5519-2

Application

FC, IP

Species Reactivity

human

Size

100 tests

Clone

MEM-158

Suggested protocols

Immunoprecipitation

Specifications

Application	FC, IP
Article No	AFC-5519-2
BioSite Brand	BioSite Flow
Clone	MEM-158
Clone Type	monoclonal
Description	Mouse Monoclonal to CD15 / Lewis x Blood Group antigen
Recommended Dilution	The purified antibody is conjugated with Peridinin-chlorophyll-protein complex (PerCP) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
Supplier	BioSite Flow
Immunogen	Human granulocytes
Isotype	IgM
Keywords	Blood Group Antigens (Human), CD and Related Antigens (Human)
Notes	CD15 (Lewis X, Le(x); stage specific embryonic antigen-1, SSEA-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids, glycoproteins and proteoglycans of various cell types, e.g. granulocytes, mast cells, monocytes, macrophages, cells of gastric mucosa, nervous system or various tumour cells. There are several variants of Lewis x, such as sialyl-Lewis x or sulphated Lewis x. Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation, based on calcium-dependent Le(x)-Le(x) interaction. This process is involved for example in embryo compaction or in autoaggregation of teratocarcinoma cells. Sialyl-Le(x) and its isomer sialyl-Le(a) are ligands of selectins. CD15 expression has been extensively used to confirm diagnosis of Hodgkin´s disease.
Product Type	Antibodies Primary
Research Area	Immunology
Size	100 tests
Species Reactivity	human
Storage	Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
Substrate / Buffer	The reagent is provided in stabilizing Tris buffered saline (TBS) solution containing 15 mM sodium azide.
Technical Specifications	The antibody MEM-158 reacts with CD15, a cell membrane molecule 3-fucosyl-N-acetyllactosamine (3-FAL) strongly expressed on granulocytes, monocytes, macrophages, mast cells; it is also present on Langerhans cells and some myeloid precursors cells.<br>_x000D_ <b>HLDA VI; WS Code AS A053</b>
Product Page Updated	2018-07-27T09:12:01.609Z

Shipping info

The delivery time for this item is approximately 5-8 business days. If other deviations occur, this will be noted on the order confirmation or communicated via email. Please note, we do reserve the right to select the best packaging and shipping method in order to insure the stability of the product and allow efficient order tracking.