Article No AFC-5157-2
Product Type Antibodies Primary
Research Area Immunology
Application FC, IP, WB
Size 100 tests


Country Availability all
BioSite Brand BioSite Flow
Clone MEM-166
Clone Type monoclonal
Conjugation PE
Description Mouse Monoclonal to CD177
Recommended Dilution The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
Supplier BioSite Flow
Immunogen Human granulocytes
Isotype IgG1
Keywords CD Antigens & MHC (Veterinary), CD and Related Antigens (Human)
Notes CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils. Its plasma membrane expression is increased during pregnancy and and inflammation or after G-CSF application. Ligand of CD177 has been identified as CD31 (PECAM-1). CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule. The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN).
Species Reactivity monkey, human
Storage Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
Substrate / Buffer The reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 15mM sodium azide.
Technical Specifications The antibody MEM-166 reacts with CD177 (Neutrophil specific antigen 1), a 60 kDa GPI-linked cell surface glycoprotein of uPAR family, expressed on granulocytes and in bone marrow early erythroblasts, megakaryocytes, promyelocytes and myelocytes. <br>_x000D_ <b>HLDA VI; WS Code M M17<br>_x000D_ HLDA VI; WS Code BP 309</b> _x000D_
Product Page Updated 2018-07-27T09:12:01.609Z

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Species reactivity:

monkey, human monkey human