Antibodies Primary

CD162

NEW
Mouse Monoclonal to CD162 / PSGL-1

Article No

AFC-5039-1

Application

FC

Species Reactivity

human

Size

100 tests

Clone

TC2

Specifications

Application FC
Article No AFC-5039-1
BioSite Brand BioSite Flow
Clone TC2
Clone Type monoclonal
Conjugation FITC
Description Mouse Monoclonal to CD162 / PSGL-1
Recommended Dilution The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary.
Supplier BioSite Flow
Immunogen Human thymocytes
Isotype IgG1
Keywords CD and Related Antigens (Human)
Notes CD162 (P-selectin glycoprotein ligand-1, PSGL-1) is a sialomucin constitutively expressed as a disulfide-linked homodimer of two 120 kDa subunits on the surface of circulating leukocytes. CD162 serves as a ligand for P- E- and L-selectin, with the highest affinity for P-selectin. It is thus involved in leukocyte rolling at the endothelial surfaces, prerequisite for firm leukocyte adhesion and subsequent transendothelial migration. CD162 also mediates leukocyte-platelet adhesion and interleukocyte contacts. Whereas serving as an adhession molecule on mature leukocytes, CD162 is a potent negative regulator of human hematopoietic progenitors.
Product Type Antibodies Primary
Research Area Immunology
Size 100 tests
Species Reactivity human
Storage Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
Substrate / Buffer The reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 15mM sodium azide.
Technical Specifications The antibody TC2 reacts with CD162, a 220 kDa type I integral membrane protein expressed as disulfide-linked homodimer (sialomucin family). CD162 is present on the most peripheral blood T lymphocytes, monocytes, granulocytes; it is also expressed on a subpopulation of B lymphocytes and CD34<sup>+</sup> bone marrow cells.
Product Page Updated 2018-07-27T09:12:01.609Z

Shipping info

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