CD28

Article No AFC-5029-1
Product Type Antibodies Primary
Research Area Immunology
Application FC, IP, WB, IHC-Fr, ICC, FA
Size 100 tests

Specifications

Country Availability all
BioSite Brand BioSite Flow
Clone CD28.2
Clone Type monoclonal
Conjugation FITC
Description Mouse Monoclonal to CD28
Recommended Dilution The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary.
Supplier BioSite Flow
Immunogen DC28.1.3.3 murine T cell hybridoma transfected with human CD28 cDNA_x000D_
Isotype IgG1
Keywords CD Antigens & MHC (Veterinary), CD and Related Antigens (Human)
Notes CD28 is the critical T cell costimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its costimulation role CD28 functions in preventing T cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader. _x000D_
Species Reactivity human, monkey
Storage Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
Substrate / Buffer The reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 15mM sodium azide.
Technical Specifications The antibody CD28.2 reacts with CD28, a disulfide-linked homodimeric type I glycoprotein (monomer of Mw 44 kDa) which is a critical costimulatory receptor of T cells.<br>_x000D_ <b>HLDA V.; WS Code 5T CD28.05</b>_x000D_
Product Page Updated 2018-07-27T09:12:01.609Z

Shipping info

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Species reactivity:

human, monkey human monkey