Antibodies Primary

CD98

NEW
Mouse Monoclonal to CD98

Article No

AFC-4959-2

Application

FC, IP, IHC

Species Reactivity

human

Size

100 tests

Clone

MEM-108

Suggested protocols

Specifications

Application FC, IP, IHC
Article No AFC-4959-2
BioSite Brand BioSite Flow
Clone MEM-108
Clone Type monoclonal
Conjugation FITC
Description Mouse Monoclonal to CD98
Recommended Dilution The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary.
Supplier BioSite Flow
Immunogen RAJI human Burkitt's lymphoma cell line
Isotype IgG1
Keywords CD and Related Antigens (Human)
Notes CD98 (4F2) is a type II transmembrane glycoprotein which serves as the heavy chain of the heterodimeric amino acid transporters (HATs). CD98, linked to various light chains by disulfide bond, is responsible for cell surface expression and basolateral localization of this transporter complex in polarized epithelial cells and also interacts with beta1 integrins and increases their affinity for ligand. Besides its roles in amino acid transport, CD98 is thus involved in cell fusion and activation. It is implicated in regulation of cellular differentiation, growth and apoptosis.
Product Type Antibodies Primary
Research Area Immunology
Size 100 tests
Species Reactivity human
Storage Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
Substrate / Buffer The reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 15mM sodium azide.
Technical Specifications The antibody MEM-108 reacts with CD98, a 125 kDa disulfide-linked heterodimer (80 kDa glycosylated heavy chain + 45 kDa non-glykosylated light chain). CD98 is expressed on T lymphocytes (upon activation) and activated NK cells; it is also present at low levels on B lymphocytes, NK cells, monocytes and platelets.<br>_x000D_ <b>HLDA VI; WS Code BP 409 <br> _x000D_ HLDA VI; WS Code NL N-L017 </b>_x000D_
Product Page Updated 2019-05-20T06:41:23.567Z

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