CD10

Article No AFC-4840-2
Product Type Antibodies Primary
Research Area Immunology
Application FC, IP
Size 0.1 mg

Specifications

Country Availability all
BioSite Brand BioSite Flow
Clone MEM-78
Clone Type monoclonal
Concentration 1 mg/ml
Conjugation Biotin
Description Mouse Monoclonal to CD10 / CALLA
Recommended Dilution The purified antibody is conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.
Supplier BioSite Flow
Immunogen NALM-6 human pre-B cell line
Isotype IgG1
Keywords CD and Related Antigens (Human)
Notes CD10 (neutral endopeptidase – NEP, common acute lymphocytic leukemia antigen – CALLA, membrane metallo-endopeptidase – MME, enkefalinase) is a 100-kDa cell surface zinc metalloprotease cleaving peptide bonds on the N-terminus of hydrophobic amino acids and inactivating multiple physiologically active peptids. CD10 is expressed on various normal cell types, including lymphoid precursor cells, germinal center B lymhocytes, and some epithelial cells, and its expression level serves as a marker for diagnostics of many carcinomas. CD10 is also a differentiation antigen for early B-lymphoid progenitors in the B-cell differentiation pathway and has a key role in regulation of growth, differentiation and signal transduction of many cellular systems.
Species Reactivity human
Storage Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.
Substrate / Buffer Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Technical Specifications The antibody MEM-78 reacts with CD10 antigen (CALLA - Common acute lymphatic leukemia antigen), a 100 kDa type II integral membrane protein. <br><b>HLDA IV; WS Code B 506<br>HLDA V; WS Code B CD10.4</b>
Product Page Updated 2018-07-27T09:12:01.609Z

Shipping info

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Species reactivity:

human human

Suggested protocols:

Immunoprecipitation

Immunoprecipitation