CD209

Article No AFC-4788-2
Product Type Antibodies Primary
Research Area Immunology
Application FC, IHC, ICC
Size 100 tests

Specifications

Country Availability all
BioSite Brand BioSite Flow
Clone UW60.1
Clone Type monoclonal
Conjugation APC
Description Mouse Monoclonal to CD209
Recommended Dilution The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
Supplier BioSite Flow
Immunogen CD209-His-tagged fusion protein
Isotype IgG1
Keywords CD and Related Antigens (Human)
Notes CD209, also known as DC-SIGN (dendritic cell-specific ICAM-3-grabbing nonintegrin) is a transmembrane receptor expressed on the surface of dendritic cells and macrophages, which recognizes numerous pathogens ranging from parasites to viruses. Its N-terminal domain is transmembrane, whereas a tandem-repeat neck domain and the C terminal C-type lectin carbohydrate recognition domain have dual function as a pathogen recognition receptor and a cell adhesion receptor. The neck region is responsible for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. A ligand of CD209 is also CD50 (ICAM-3).
Species Reactivity human
Storage Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
Substrate / Buffer The reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 15mM sodium azide.
Technical Specifications The mouse monoclonal antibody UW60.1 recognizes human CD209 (DC-SIGN), a 44 kDa transmembrane receptor expressed on the surface of dendritic cells and macrophages.
Product Page Updated 2018-07-27T09:12:01.609Z

Shipping info

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Species reactivity:

human human

Suggested protocols:

IHC-P

IHC-P