Article No
AFC-TMN89G-100
Application | FC |
Article No | AFC-TMN89G-100 |
Biosite Brand | Biosite Flow |
Country Availability | all |
Clone | M38 |
Clone Type | monoclonal |
Conjugation | APC |
Description | Anti-Hu CD81 APC |
Recommended Dilution | The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary. |
Supplier | Nordic Biosite |
Entrez Gene ID | 975 |
Format | APC |
Immunogen | MOLT-4 (human T-ALL cell line) |
Isotype | IgG1 |
Keywords | CD Antigens & MHC (Veterinary), CD and Related Antigens (Human) |
Notes | CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells, e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus. |
Alias Names | S5.7, CVID6, TAPA1, TSPAN28 |
Previous Article No | AFC-4762-2 |
Product Type | Antibodies Primary |
Protocol | Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. |
Purification | Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography. |
Research Area | Immunology |
Size | 100 tests |
Source / Host | mouse |
Species Reactivity | rabbit, cat/feline, human |
Storage | Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze. |
Substrate / Buffer | Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
Technical Specifications | The antibody M38 reacts with an extracellular epitope of CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells. |
UniProt Number | P60033 |
Product Page Updated | 2024-01-03T12:18:20.318Z |