CD81

Article No AFC-4762-2
Product Type Antibodies Primary
Research Area Immunology
Application FC, IP, WB, IHC-P, ICC, FA
Size 100 tests

Specifications

Country Availability all
BioSite Brand BioSite Flow
Clone M38
Clone Type monoclonal
Conjugation APC
Description Mouse Monoclonal to CD81
Recommended Dilution The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
Supplier BioSite Flow
Immunogen MOLT-4 (human T-ALL cell line)_x000D_
Isotype IgG1
Keywords CD Antigens & MHC (Veterinary), CD and Related Antigens (Human)
Notes CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells – e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus.
Species Reactivity human, cat/feline, rabbit
Storage Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
Substrate / Buffer The reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 15mM sodium azide.
Technical Specifications The antibody M38 reacts with CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells._x000D_
Product Page Updated 2018-07-27T09:12:01.609Z

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Species reactivity:

human, cat/feline, rabbit human rabbit