CD56

Article No AFC-4711-2
Product Type Antibodies Primary
Research Area Immunology
Application FC, IP, IHC
Size 100 tests

Specifications

Country Availability all
BioSite Brand BioSite Flow
Clone MEM-188
Clone Type monoclonal
Conjugation APC
Description Mouse Monoclonal to CD56 / NCAM
Recommended Dilution The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
Supplier BioSite Flow
Immunogen KG-1 human acute myelogenous leukemia cell line
Isotype IgG2a
Keywords CD Antigens & MHC (Veterinary), CD and Related Antigens (Human)
Notes CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of immunoglobulin family serving as adhesive molecule which is ubiquitously expressed in nervous system, usually as 120 kDa, 140 kDa or 180 kDa isoform, and it is also found on T cells and NK cells. Polysialic modification results in reduction of CD56-mediated cell adhesion and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumours and ovarian granulosa cell tumours.
Species Reactivity human, monkey
Storage Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
Substrate / Buffer The reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 15mM sodium azide.
Technical Specifications The antibody MEM-188 reacts with a 180 kDa isoform of CD56 (NCAM) expressed in leukocytes. It has been suggested that the antibody MEM-188 could react with rhesus monkey lymphocytes. Reactivity with other NCAM isoforms has not been tested. <br>_x000D_ <b>HLDA VI; WS code A055<br>_x000D_ HLDA VI; WS Code NK26<br>_x000D_ HLDA VII; WS code 70077</b>
Product Page Updated 2019-05-20T06:41:23.567Z

Shipping info

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Species reactivity:

human, monkey human monkey

Suggested protocols:

Immunoprecipitation

Immunoprecipitation

IHC-P

IHC-P