CD48

Article No AFC-4710-2
Product Type Antibodies Primary
Research Area Immunology
Application FC, IP, WB, IHC
Size 100 tests

Specifications

Country Availability all
BioSite Brand BioSite Flow
Clone MEM-102
Clone Type monoclonal
Conjugation APC
Description Mouse Monoclonal to CD48 / BLAST-1
Recommended Dilution The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
Supplier BioSite Flow
Immunogen Raji human Burkitt's lymphoma cell line
Isotype IgG1
Keywords CD Antigens & MHC (Veterinary), CD and Related Antigens (Human)
Notes CD48 (Blast-1) belongs to the CD2 subset of the Ig superfamily, which includes CD2, CD2F-10, CD58, CD84, CD150, CD229, CD244 and others. These molecules bind to the same or another members of their family, thus mediate homotypic or heterotypic adhesion. CD48 is a GPI-anchored protein broadly expressed on hematopoietic cells and serves as a high affinity ligand for 2B4 and low affinity ligand for CD2. 2B4-CD48 interaction among NK cells and NK-T cells regulates cell proliferation. Signaling through CD48 results in eosinophil activation and CD48 expression is increased in several infectious diseases.
Species Reactivity human, monkey
Storage Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
Substrate / Buffer The reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 15mM sodium azide.
Technical Specifications The antibody MEM-102 reacts with CD48 antigen (Blast-1), a 40-47 kDa GPI-anchored membrane protein (immunoglobulin supergene family) widely expressed on hematopoietic cells; it is negative on granulocytes, platelets and erythrocytes.<br>_x000D_ <b>HLDA V; WS Code AS S014</b>
Product Page Updated 2019-05-20T06:41:23.567Z

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Species reactivity:

human, monkey human monkey