NK1.1 / CD161bc (mouse)
Specifications
| Country Availability | all |
| BioSite Brand | BioSite Flow |
| Clone | PK136 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | Mouse Monoclonal to NK1.1 / CD161bc (mouse) |
| Supplier | BioSite Flow |
| Immunogen | NK1-positive murine splenic and bone marrow cells |
| Isotype | IgG2a |
| Keywords | CD and Related Antigens & MHC (Rodent) |
| Notes | NK1.1 / CD161bc (also known as NKRP1, Ly55c, or Ly59) is a cell surface antigen expressed on NK cells and NK-T cells of certain mouse strains, which is being used for identification or antibody-mediated depletion of these cells in the respective strains. This antigen participates in NK cell activation, including production of interferon gamma, and release of cytotoxic granules. |
| Purification | Purified by protein-A affinity chromatography |
| Purity | > 95% (by SDS-PAGE) |
| Species Reactivity | mouse |
| Storage | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label. |
| Substrate / Buffer | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 |
| Technical Specifications | The mouse monoclonal antibody PK136 recognizes NK1.1 antigen (NK cell marker) expressed by some mouse strains (e.g. C57BL/6, NZB, CE, C58, Ma/My), whereas other strains (e.g. BALB/c, AKR, CBA, C3H) do not express this antigen. This antibody detects a conformational epitope on Nkrp1c and Nkrp1b gene products. |
| Product Page Updated | 2018-07-27T09:12:01.609Z |
Shipping info
The delivery time for this item is approximately 5-8 business days. If other deviations occur, this will be noted on the order confirmation or communicated via email. Please note, we do reserve the right to select the best packaging and shipping method in order to insure the stability of the product and allow efficient order tracking.
Species reactivity:
mouse
Suggested protocols:
Immunoprecipitation