Article No
AFC-ND5CKU-0.1
Anti-Hu CD94 Purified
Anti-Hu CD94 Purified
Antibodies Primary
Specifications
| Application | FC |
| Article No | AFC-ND5CKU-0.1 |
| Biosite Brand | Biosite Flow |
| Country Availability | all |
| Clone | HP-3D9 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | Anti-Hu CD94 Purified |
| Supplier | Nordic Biosite |
| Entrez Gene ID | 3824 |
| Format | Purified |
| Immunogen | Cultured human NK cells |
| Isotype | IgG1 k |
| Keywords | CD and Related Antigens (Human) |
| Notes | CD94, also known as KLRD1 (killer cell lectin-like receptor D1), is a transmembrane glycoprotein of the C-type lectin family, which forms disulfide-linked heterodimers with NKG2A, B, C, E, H proteins, constituting functionally distinct receptors of NK cells and related cell types. CD94/NKG2A and CD94/NKG2B heterodimers serve as inhibitory, whereas CD94/NKG2C and CD94/NKG2E as activating receptors. The ligand for CD94/NKG2 complexes has been identified as HLA-E. Extent of CD94 expression on NK cell surface can be used to demonstrate their progress through the differentiation process. |
| Alias Names | KLR-D1, KLRD1, KCLLRD1 |
| Previous Article No | AFC-4568-2, AFC-ND5CKU-0.1 |
| Product Type | Antibodies Primary |
| Protocol | Flow cytometry: Recommended dilution: 1-4 μg/ml. |
| Purification | Purified by protein-A affinity chromatography. |
| Purity | > 95% (by SDS-PAGE) |
| Research area | Immunology |
| Size | 0.1 mg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | Store at 2-8°C. Do not freeze. |
| Substrate / Buffer | Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Technical Specifications | The mouse monoclonal antibody HP-3D9 recognizes an extracellular epitope of CD94, a 70 kDa type II transmembrane glycoprotein expressed on NK cells, NK-T cells, and subsets of CD8+ T cells and gamma/delta T cells. |
| UniProt Number | Q13241 |
| Product Page Updated | 2024-01-03T12:18:20.318Z |
