Article No
AFC-FWCNUL-0.1
Specifications
| Application | IP, WB, ICC |
| Article No | AFC-FWCNUL-0.1 |
| Biosite Brand | Biosite Flow |
| Country Availability | all |
| Clone | TFG-03 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | Anti-TFG Purified |
| Supplier | Nordic Biosite |
| Entrez Gene ID | 10342 |
| Format | Purified |
| Immunogen | Human recombinant protein Trx-his-NTFG |
| Isotype | IgG2b |
| Keywords | Adaptor Proteins (Human) |
| Notes | TFG (TRK-fused gene protein) is a regulatory protein with not fully understood function. Its defects are associated with various carcinomas, such as e.g. melanoma, thyroid papillary carcinoma, or glioma. TFG structure (multiple protein interaction motifs) indicated it can be an adaptor protein. It has been demonstrated TFG interacts with proteins modulating the NFkappaB pathway (TANK and NEMO). TNG enhances the effect of TNFalpha, TANK, TRAF2 and TRAF6 in inducing NFkappaB activity. |
| Alias Names | TF6, TRKT3, SPG57 |
| Previous Article No | AFC-4556-2, AFC-FWCNUL-0.1 |
| Product Type | Antibodies Primary |
| Protocol | Flow cytometry: Recommended dilution: 1-5 μg/ml. |
| Purification | Purified by protein-A affinity chromatography. |
| Purity | > 95% (by SDS-PAGE) |
| Research area | Immunology |
| Size | 0.1 mg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | Store at 2-8°C. Do not freeze. |
| Substrate / Buffer | Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Technical Specifications | The mouse monoclonal antibody TFG-03 recognizes TFG, an approximately 50 kDa intracellular protein with regulatory functions. |
| UniProt Number | Q92734 |
| Product Page Updated | 2024-01-03T12:18:20.318Z |
